Off-label drugs for weight management

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Off-label drugs for weight management

The global pandemic of obesity and overweight now affects between 2.8 and 3.5 billion of the world population and shows no signs of abatement. Treatment for what is now recognized as a chronic disease includes pharmacotherapy, considered an essential component of comprehensive therapy. New drug discovery is robust, but the pace of the US Food and Drug Administration approval for obesity drugs h...

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Off-label uses of drugs in children.

As we approach the new millennium, very little has changed regarding the labeling of prescription drugs for use in infants and children. Along with pregnant women, infants and children remain therapeutic orphans. This condition is understandable because there are very few therapeutic indications that are unique to this patient population and the absolute quantities of drugs required by these pa...

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Off-label use of drugs in children.

The passage of the Best Pharmaceuticals for Children Act and the Pediatric Research Equity Act has collectively resulted in an improvement in rational prescribing for children, including more than 500 labeling changes. However, off-label drug use remains an important public health issue for infants, children, and adolescents, because an overwhelming number of drugs still have no information in ...

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off-label and off-nccn guidelines uses of antineoplastic drugs in china.

to evaluate off-label and off-nccn guidelines uses of antineoplastic drugs in a major chinese hospital.totally 1122 patients were selected from july to december 2011. then, the off-label and off-nccn guidelines uses of antineoplastic drugs were analyzed.in 798 of 1122 patients (71.12%), drugs were used for off-label. in 317 of 1122 patients (28.25%), the drugs were prescribed for off-label and ...

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Unlicensed and off-label prescription of respiratory drugs to children.

Many respiratory drugs are not available in formulations suitable for infants and toddlers. Efficacy and safety research is mostly restricted to older children. However, respiratory drugs are frequently used in children for common diseases like asthma, upper and lower respiratory tract infections, rhinitis and sinusitis. The unlicensed and off-label use of respiratory drugs in children were stu...

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ژورنال

عنوان ژورنال: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy

سال: 2017

ISSN: 1178-7007

DOI: 10.2147/dmso.s95299